Analytical Data
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基因名
CES1G
- Application
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别名
CES1G；Ces1g；Liver carboxylesterase 1
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3UW56
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表达区间
1-565aa
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氨基酸序列
MWLCALSLISLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLGDHADELFSVWGAPFLKEGASEEEINLSKMVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGVPAQAAHRLKDKEVDFWTELRAKETAERSSHREHVEL
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CES1G is a protein belonging to the carboxylesterase family, which plays a crucial role in the hydrolysis and metabolism of various esters and lipids. The study of CES1G has garnered significant attention due to its potential implications in pharmacology and toxicology, particularly in the metabolism of drug compounds and environmental pollutants. Research has shown that CES1G is involved in the detoxification processes, influencing the pharmacokinetics of therapeutic agents and the activity of pro-drugs. Moreover, variations in CES1G expression and activity can lead to interindividual differences in drug responses and adverse effects, making it a critical focus in personalized medicine. Understanding the structure, function, and regulation of CES1G can provide insights into its role in metabolic pathways and help identify novel therapeutic targets, especially in relation to diseases associated with metabolic dysregulation. Additionally, the exploration of CES1G in agricultural biochemistry highlights its importance in the biodegradation of pesticide residues, thus contributing to ecological safety. Overall, research on CES1G is pivotal for advancing our knowledge of metabolic processes and enhancing drug design and environmental sustainability efforts.
