Analytical Data
-
Gene name
BDH1
- Application
-
Alternative Names
BDH1；BDH；SDR9C1；D-beta-hydroxybutyrate dehydrogenase. mitochondrial
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q02338
-
Expression Region
1-343aa
-
AA Sequence
MGSSHHHHHHSSGLVPRGSHMLATRLSRPLSRLPGKTLSACDRENGARRP LLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFALAKHLHSKGF LVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSS LKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL PLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLG VKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEK IAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMT HLPGAISDMIYIR
-
Molecular Weight
40 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BDH1 (butyric acid dehydrogenase 1) is an enzyme that plays a crucial role in the metabolism of butyrate and other short-chain fatty acids, which are significant for maintaining gut health and overall metabolic functions. The study of BDH1 has gained momentum due to its potential implications in various diseases, including metabolic disorders, cancer, and inflammatory bowel diseases. Research has demonstrated that BDH1 is involved in cellular signaling pathways and can influence the energy homeostasis of cells. Furthermore, the manipulation of BDH1 activity presents new avenues for therapeutic strategies, especially in conditions characterized by dysregulated energy metabolism. Recombinant BDH1 protein generation allows for a deeper understanding of its biochemical properties and functional roles in various physiological contexts. This research not only aims to elucidate the enzyme's mechanism of action but also to explore its potential as a biomarker for disease progression and as a target for innovative treatment options. As the scientific community progresses in the characterization and application of BDH1, it is anticipated that findings will contribute significantly to the development of novel interventions and enhance our comprehension of its broader impact on human health.
