Analytical Data
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基因名
BDH1
- Application
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别名
BDH1；BDH；SDR9C1；D-beta-hydroxybutyrate dehydrogenase. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q02338
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表达区间
1-343aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMLATRLSRPLSRLPGKTLSACDRENGARRP LLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFALAKHLHSKGF LVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSS LKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL PLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLG VKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEK IAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMT HLPGAISDMIYIR
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BDH1 (butyric acid dehydrogenase 1) is an enzyme that plays a crucial role in the metabolism of butyrate and other short-chain fatty acids, which are significant for maintaining gut health and overall metabolic functions. The study of BDH1 has gained momentum due to its potential implications in various diseases, including metabolic disorders, cancer, and inflammatory bowel diseases. Research has demonstrated that BDH1 is involved in cellular signaling pathways and can influence the energy homeostasis of cells. Furthermore, the manipulation of BDH1 activity presents new avenues for therapeutic strategies, especially in conditions characterized by dysregulated energy metabolism. Recombinant BDH1 protein generation allows for a deeper understanding of its biochemical properties and functional roles in various physiological contexts. This research not only aims to elucidate the enzyme's mechanism of action but also to explore its potential as a biomarker for disease progression and as a target for innovative treatment options. As the scientific community progresses in the characterization and application of BDH1, it is anticipated that findings will contribute significantly to the development of novel interventions and enhance our comprehension of its broader impact on human health.
