Analytical Data
-
Gene name
MEF2A
- Application
-
Alternative Names
MEF2A；MEF2；Myocyte-specific enhancer factor 2A
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q02078-5
-
Expression Region
1-499aa
-
AA Sequence
MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS SNKLFQYAST DMDKVLLKYT EYNEPHESRT NSDIVEALNK KEHRGCDSPD PDTSYVLTPH TEEKYKKINE EFDNMMRNHK IAPGLPPQNF SMSVTVPVTS PNALSYTNPG SSLVSPSLAA SSTLTDSSML SPPQTTLHRN VSPGAPQRPP STGNAGGMLS TTDLTVPNGA GSSPVGNGFV NSRASPNLIG ATGANSLGKV MPTKSPPPPG GGNLGMNSRK PDLRVVIPPS SKGMMPPLNT QRISSSQATQ PLATPVVSVT TPSLPPQGLV YSAMPTAYNT DYSLTSADLS ALQGFNSPGM LSLGQVSAWQ QHHLGQAALS SLVAGGQLSQ GSNLSINTNQ NISIKSEPIS PPRDRMTPSG FQQQQQQQQQ QQPPPPPQPQ PQPPQPQPRQ EMGRSPVDSL SSSSSSYDGS DREDPRGDFH SPIVLGRPPN TEDRESPSVK RMRMDAWVT
-
Molecular Weight
55 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MEF2A (Myocyte Enhancer Factor 2A) is a member of the MEF2 family of transcription factors, which play crucial roles in muscle development, differentiation, and cellular response to stress. Research into MEF2A has gained significant attention due to its implications in various biological processes, including cardiogenesis, neurogenesis, and the regulation of gene expression in response to physiological stimuli. Abnormalities in MEF2A function have been linked to multiple diseases, such as cardiac hypertrophy, neurodegenerative disorders, and cancer. As MEF2A is involved in pathways that govern the survival and apoptosis of cells, understanding its structure and function is critical for elucidating its role in disease mechanisms. Recombinant MEF2A proteins are generated to study their biological functions, interaction partners, and regulatory mechanisms in vitro and in vivo. By producing and characterizing these proteins, researchers aim to provide insights into the molecular pathways involving MEF2A, identify potential therapeutic targets, and develop strategies for modulating its activity in disease contexts. Given its central role in numerous cellular processes and its potential as a therapeutic target, the study of MEF2A recombinant proteins constitutes an essential avenue of biomedical research, contributing to our understanding of fundamental cellular mechanisms and potential interventions in related pathologies.
