Cat: PA1000-316DB

Recombinant Human BCL7C Protein,His

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Analytical Data

  • Gene name

    BCL7C

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BCL7C;B-cell CLL/lymphoma 7 Protein family member C

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8WUZ0

  • Expression Region

    1-217aa

  • AA Sequence

    MGSSHHHHHHSSGLVPRGSHMGSMAGRTVRAETRSRAKDDIKKVMATIEK VRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGR GASPRGGGPLILLDLNDENSNQSFHSEGSLQKGTEPSPGGTPQPSRPVSP AGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAEA PEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP

  • Molecular Weight

    26 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

BCL7C (B-cell lymphoma 7 protein C) is a member of the BCL7 gene family, which plays a significant role in cellular processes such as cell proliferation, differentiation, and apoptosis. Its involvement in various cancers, particularly hematological malignancies and solid tumors, has drawn significant attention to understanding its molecular mechanisms. Researchers have identified that BCL7C is often implicated in chromosomal rearrangements and translocations, contributing to oncogenesis. The study of BCL7C recombinant protein serves as a crucial tool for elucidating its biological functions and potential therapeutic roles. By producing and characterizing recombinant BCL7C, scientists aim to investigate its interactions with other proteins, its influence on cell cycle regulation, and its impact on tumorigenesis. Furthermore, understanding the structure-function relationship of BCL7C can provide insights into its role in cancer biology and aid in the development of novel strategies for targeted therapies. Overall, the research on BCL7C recombinant protein is essential for unveiling the complexities of cancer mechanisms and identifying potential biomarkers for diagnosis and treatment.

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