Analytical Data
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基因名
ACTC1
- Application
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别名
ACTC1；ACTC；Actin. alpha cardiac muscle 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P68032
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表达区间
3-377aa
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氨基酸序列
DDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
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分子量
47.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ACTC1, or actin alpha cardiac muscle 1, is a key protein predominantly found in cardiac and skeletal muscle tissues. It plays a crucial role in muscle contraction and cellular architecture by contributing to the structural framework of the cytoskeleton. Mutations in the ACTC1 gene have been linked to various cardiomyopathies, highlighting its significance in cardiac health. Research into recombinant ACTC1 protein has gained momentum in recent years, driven by the need to understand the molecular mechanisms underlying cardiac diseases and to develop potential therapeutic strategies. By producing recombinant ACTC1 in vitro, scientists can explore its biochemical properties, interaction with other proteins, and the effects of specific mutations on its function. This research not only enhances our understanding of muscle biology but also provides insights into the pathophysiology of heart diseases, paving the way for innovative diagnostic and treatment options. As a result, ACTC1 and its recombinant derivatives are becoming increasingly important in both fundamental research and clinical applications, making it a focal point for studies aimed at unraveling the complexities of cardiac muscle disorders.
