Analytical Data
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Gene name
FILIP1
- Application
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Alternative Names
Filamin-A-interacting protein 1; FILIP; FILIP1; FLIP1_HUMAN
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z7B0
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Expression Region
71-260aa
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Molecular Weight
30.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FILIP1 (Filamin A-Interacting Protein 1) is a member of the cytoskeletal protein family that plays a critical role in various cellular processes, including signal transduction, cell adhesion, and the regulation of the actin cytoskeleton. Initial studies have identified FILIP1 as a protein that interacts with filamin A, a key player in maintaining cell structure and integrity. Given its involvement in cytoskeletal dynamics, researchers have begun exploring FILIP1's potential implications in cell motility and tissue development. Moreover, recent investigations highlight its significance in cancer biology, as altered expression levels of FILIP1 have been linked to tumor progression and metastasis. Understanding the role of FILIP1 in these processes could provide insights into novel therapeutic strategies for cancer treatment. The production and characterization of recombinant FILIP1 protein are essential for advancing our knowledge of its biological functions. By using techniques such as cloning, expression in suitable host cells, and purification methods, scientists can study the biochemical properties of FILIP1 and its interactions with other proteins. These studies are expected to further elucidate the mechanisms by which FILIP1 influences cell behavior and contribute to the broader understanding of cytoskeletal regulation in health and disease. Overall, the ongoing research into FILIP1 not only enhances our comprehension of fundamental cellular processes but also holds promise for developing targeted interventions in cancer and other diseases associated with cytoskeletal dysregulation.
