Analytical Data
-
Gene name
ATP5C1
- Application
-
Alternative Names
ATP5C1;ATP5C;ATP5C1;ATP5CL1;ATP synthase subunit gamma. mitochondrial
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P36542
-
Expression Region
26-298aa
-
AA Sequence
ATLKD ITRRLKSIKN IQKITKSMKM VAAAKYARAE RELKPARIYG LGSLALYEKA DIKGPEDKKK HLLIGVSSDR GLCGAIHSSI AKQMKSEVAT LTAAGKEVML VGIGDKIRGI LYRTHSDQFL VAFKEVGRKP PTFGDASVIA LELLNSGYEF DEGSIIFNKF RSVISYKTEE KPIFSLNTVA SADSMSIYDD IDADVLQNYQ EYNLANIIYY SLKESTTSEQ SARMTAMDNA SKNASEMIDK LTLTFNRTRQ AVITKELIEI ISGAAALD
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ATP5C1, a subunit of ATP synthase, plays a crucial role in cellular energy metabolism by facilitating ATP production in mitochondria. The gene encoding ATP5C1 has garnered attention due to its involvement in various metabolic disorders and potential implications in cancer biology. Research indicates that dysregulation of ATP5C1 can impact mitochondrial function and energy homeostasis, contributing to the pathology of diseases such as neurodegenerative disorders and certain types of cancer. Furthermore, ATP5C1's expression levels have been linked to the aggressiveness of tumors, positioning it as a potential biomarker for cancer prognosis. Studies on recombinant ATP5C1 proteins aim to elucidate its structural and functional properties, which can provide insights into its role in ATP synthesis and reveal potential therapeutic targets. The recombinant expression of ATP5C1 allows for a detailed investigation of its enzymatic activity, interaction with other mitochondrial components, and regulatory mechanisms. Understanding these aspects could pave the way for novel strategies to manipulate energy metabolism in disease contexts, making ATP5C1 a significant focus of ongoing biochemical research.











