Cat: PA1000-9061

Recombinant Human FSIP1 Protein,His

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Analytical Data

  • Gene name

    FSIP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FSIP1;Fibrous sheath-interacting Protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NA03

  • Expression Region

    1-581aa

  • AA Sequence

    MDIIKGNLDG ISKPASNSRI RPGSRSSNAS LEVLSTEPGS FKVDTASNLN SGKEDHSESS NTENRRTSND DKQESCSEKI KLAEEGSDED LDLVQHQIIS ECSDEPKLKE LDSQLQDAIQ KMKKLDKILA KKQRREKEIK KQGLEMRIKL WEEIKSAKYS EAWQSKEEME NTKKFLSLTA VSEETVGPSH EEEDTFSSVF HTQIPPEEYE MQMQKLNKDF TCDVERNESL IKSGKKPFSN TEKIELRGKH NQDFIKRNIE LAKESRNPVV MVDREKKRLV ELLKDLDEKD SGLSSSEGDQ SGWVVPVKGY ELAVTQHQQL AEIDIKLQEL SAASPTISSF SPRLENRNNQ KPDRDGERNM EVTPGEKILR NTKEQRDLHN RLREIDEKLK MMKENVLEST SCLSEEQLKC LLDECILKQK SIIKLSSERK KEDIEDVTPV FPQLSRSIIS KLLNESETKV QKTEVEDADM LESEECEASK GYYLTKALTG HNMSEALVTE AENMKCLQFS KDVIISDTKD YFMSKTLGIG RLKRPSFLDD PLYGISVSLS SEDQHLKLSS PENTIADEQE TKDAAEECKE P

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

FSIP1 (Fibrous sheath interacting protein 1) is a protein that has garnered attention due to its critical role in sperm maturation and fertility. Located predominantly in the fibrous sheath of the sperm tail, FSIP1 is implicated in the structural and functional integrity of spermatozoa. Studies have suggested that mutations or alterations in the expression of FSIP1 may lead to severe male infertility, highlighting its importance in reproductive biology. Moreover, FSIP1 is currently being investigated for its potential involvement in various cellular processes, including cell signaling and cancer progression. The recombinant expression of FSIP1 offers a promising approach to better understand its function, interactions with other proteins, and its molecular mechanisms in both normal and pathological states. Researchers are utilizing recombinant techniques to produce FSIP1 for biochemical assays, structural biology studies, and potential therapeutic applications. Understanding the detailed role of FSIP1 could not only shed light on male reproductive health but also provide insights into broader biological mechanisms where FSIP1's functions may be relevant.

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