Analytical Data
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Gene name
ATP1B2
- Application
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Alternative Names
ATP1B2；Sodium/potassium-transporting ATPase subunit beta-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P14415
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Expression Region
68-290aa
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AA Sequence
DHTPKYQDRL ATPGLMIRPK TENLDVIVNV SDTESWDQHV QKLNKFLEPY NDSIQAQKND VCRPGRYYEQ PDNGVLNYPK RACQFNRTQL GNCSGIGDST HYGYSTGQPC VFIKMNRVIN FYAGANQSMN VTCAGKRDED AENLGNFVMF PANGNIDLMY FPYYGKKFHV NYTQPLVAVK FLNVTPNVEV NVECRINAAN IATDDERDKF AGRVAFKLRI NKT
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Molecular Weight
28 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ATP1B2, a member of the ATPase Na+/K+ transporting beta subunit family, is crucial for maintaining ionic homeostasis in cellular environments by interacting with the alpha subunit and facilitating the activity of the Na+/K+ ATPase pump. This pump plays a vital role in regulating cell membrane potential and is essential for various physiological processes, including muscle contraction, nerve impulse transmission, and nutrient uptake. Research has shown that mutations or dysregulation of ATP1B2 can lead to pathological conditions, such as hypertension and neurological disorders. Recombinant ATP1B2 protein has been produced to study its structural and functional properties, providing insights into its role in health and disease. Such studies utilize various expression systems to obtain sufficient quantities of the protein, allowing for detailed biochemical assays, interaction studies, and investigations into the functional consequences of specific mutations. The exploration of ATP1B2’s mechanism of action and its potential as a therapeutic target underscores its significance in cellular physiology and offers avenues for developing innovative treatments for related disorders.
