Analytical Data
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基因名
Klra3
- Application
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别名
5E6 Lymphocyte antigen 49c Short name: Ly-49c Nk2.1 T-cell surface glycoprotein Ly-49C Ly-49c, Ly49C
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种属
Mouse
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q64329
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表达区间
70-266aa
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分子量
27.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Klra3, a member of the Ly49 gene family, encodes a receptor primarily expressed on natural killer (NK) cells and some T cells in mice. This receptor plays a critical role in the immune response, particularly in recognizing and eliminating virally infected or tumor cells. Studies have shown that Klra3 can modulate NK cell activity through interaction with major histocompatibility complex (MHC) class I molecules. Research on Klra3 recombinant proteins aims to elucidate its structural and functional characteristics, contributing to a deeper understanding of NK cell biology and immune regulation. Investigating Klra3 can provide insights into its signaling pathways, ligand interactions, and potential therapeutic applications in immunotherapy and cancer treatment. The development of recombinant Klra3 proteins can facilitate the study of its antigen specificity and pave the way for novel targeted therapies that enhance NK cell efficacy against malignancies. Furthermore, understanding Klra3's role in the context of immune evasion by tumors could lead to innovative strategies to overcome resistance in cancer therapies, making it a significant focus in immunological research.
