Analytical Data
-
Gene name
Klra3
- Application
-
Alternative Names
5E6 Lymphocyte antigen 49c Short name: Ly-49c Nk2.1 T-cell surface glycoprotein Ly-49C Ly-49c, Ly49C
-
Species
Mouse
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q64329
-
Expression Region
70-266aa
-
Molecular Weight
27.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Klra3, a member of the Ly49 gene family, encodes a receptor primarily expressed on natural killer (NK) cells and some T cells in mice. This receptor plays a critical role in the immune response, particularly in recognizing and eliminating virally infected or tumor cells. Studies have shown that Klra3 can modulate NK cell activity through interaction with major histocompatibility complex (MHC) class I molecules. Research on Klra3 recombinant proteins aims to elucidate its structural and functional characteristics, contributing to a deeper understanding of NK cell biology and immune regulation. Investigating Klra3 can provide insights into its signaling pathways, ligand interactions, and potential therapeutic applications in immunotherapy and cancer treatment. The development of recombinant Klra3 proteins can facilitate the study of its antigen specificity and pave the way for novel targeted therapies that enhance NK cell efficacy against malignancies. Furthermore, understanding Klra3's role in the context of immune evasion by tumors could lead to innovative strategies to overcome resistance in cancer therapies, making it a significant focus in immunological research.
