Analytical Data
-
Gene name
ASGR2
- Application
-
Alternative Names
ASGR2；CLEC4H2；AsialoglycoProtein receptor 2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P07307
-
Expression Region
80-311aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSQSEGHRG AQLQAELRSL KEAFSNFSSS TLTEVQAIST HGGSVGDKIT SLGAKLEKQQ QDLKADHDAL LFHLKHFPVD LRFVACQMEL LHSNGSQRTC CPVNWVEHQG SCYWFSHSGK AWAEAEKYCQ LENAHLVVIN SWEEQKFIVQ HTNPFNTWIG LTDSDGSWKW VDGTDYRHNY KNWAVTQPDN WHGHELGGSE DCVEVQPDGR WNDDFCLQVY RWVCEKRRNA TGEVA
-
Molecular Weight
29 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ASGR2 (asialoglycoprotein receptor 2) is a crucial membrane protein predominantly expressed in the liver, playing a key role in the clearance of asialoglycoproteins from circulation. It is known to interact with various glycoproteins and holds significance in both physiological and pathological processes, including liver function and immune response. Due to its involvement in hepatic metabolism and potential implications in liver diseases and cancer, ASGR2 has emerged as a target for therapeutic interventions. The study of ASGR2 recombinant proteins facilitates a better understanding of its structure-function relationship and paves the way for developing diagnostic tools and targeted therapies. Recombinant ASGR2 can be produced using advanced biotechnological methods, allowing for detailed studies on receptor binding properties and signal transduction pathways. Exploring the functional characteristics of ASGR2 through recombinant protein studies can yield insights into its role in cellular communication, its mechanism as a facilitator of endocytosis, and its potential association with disease states. Furthermore, understanding ASGR2 could contribute to the development of novel strategies for drug delivery, particularly in liver-targeted therapies. As research progresses, the elucidation of ASGR2's structural features and interaction dynamics will enhance our comprehension of liver physiology and pathology, ultimately supporting the development of innovative clinical applications.
