Analytical Data
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基因名
ARL5A
- Application
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别名
ARL5A；ARFLP5；ARL5；ADP-ribosylation factor-like Protein 5A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y689
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表达区间
1-179aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMGILFTRIWRLFNHQEHKVIIVGLDN AGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDIGGQESLRSS WNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANK QDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRL KIR
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARL5A (ADP-ribosylation factor-like 5A) is a small GTPase that plays a critical role in various cellular processes, including vesicular trafficking and signal transduction. Its involvement in the regulation of membrane dynamics and intracellular transport makes it a significant target for understanding cellular function and disease mechanisms. Recent studies have suggested that ARL5A may be linked to cancer progression, neurodegenerative diseases, and other pathological conditions, highlighting its potential as a biomarker and therapeutic target. The recombinant protein of ARL5A is essential for elucidating its structure-function relationship, allowing researchers to investigate its GTPase activity, interaction with other cellular proteins, and roles in various signaling pathways. By expressing and purifying ARL5A as a recombinant protein, scientists can conduct biophysical and biochemical analyses to characterize its properties, which is critical for developing strategies to manipulate its activity in disease contexts. The growing interest in ARL5A further emphasizes the need for in-depth research into its biological functions, interactions, and potential involvement in therapeutic interventions, making it a focal point for future studies in cell biology and drug discovery.
