Analytical Data
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Gene name
WNT5B
- Application
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Alternative Names
WNT5B；Protein Wnt-5b
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H1J7
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Expression Region
18-359aa
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AA Sequence
QLL TDANSWWSLA LNPVQRPEMF IIGAQPVCSQ LPGLSPGQRK LCQLYQEHMA YIGEGAKTGI KECQHQFRQR RWNCSTADNA SVFGRVMQIG SRETAFTHAV SAAGVVNAIS RACREGELST CGCSRTARPK DLPRDWLWGG CGDNVEYGYR FAKEFVDARE REKNFAKGSE EQGRVLMNLQ NNEAGRRAVY KMADVACKCH GVSGSCSLKT CWLQLAEFRK VGDRLKEKYD SAAAMRVTRK GRLELVNSRF TQPTPEDLVY VDPSPDYCLR NESTGSLGTQ GRLCNKTSEG MDGCELMCCG RGYNQFKSVQ VERCHCKFHW CCFVRCKKCT EIVDQYICK
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WNT5B, a member of the Wnt signaling pathway, has garnered significant attention in recent years due to its pivotal role in various biological processes, including development, cell differentiation, and tissue regeneration. This glycoprotein, encoded by the WNT5B gene, is involved in non-canonical Wnt signaling, which influences cellular movements and the organization of tissues during embryogenesis. Aberrant expression of WNT5B has been implicated in several pathological conditions, such as cancer metastasis, where it modulates the tumor microenvironment and contributes to malignant behaviors like invasion and migration. Researchers have explored the potential of recombinant WNT5B protein to better understand its molecular mechanisms and investigate its therapeutic applications. Producing WNT5B as a recombinant protein allows for more detailed studies on its interactions with receptors and downstream signaling pathways, offering insights into its role in both normal physiology and disease. Furthermore, as a potential target for drug development, recombinant WNT5B may provide novel strategies for therapeutic interventions in cancers and regenerative medicine. Overall, the study of recombinant WNT5B protein holds promise not only for advancing our understanding of Wnt signaling dynamics but also for developing innovative treatment approaches for various diseases.
