Analytical Data
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基因名
WNT5B
- Application
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别名
WNT5B；Protein Wnt-5b
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H1J7
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表达区间
18-359aa
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氨基酸序列
QLL TDANSWWSLA LNPVQRPEMF IIGAQPVCSQ LPGLSPGQRK LCQLYQEHMA YIGEGAKTGI KECQHQFRQR RWNCSTADNA SVFGRVMQIG SRETAFTHAV SAAGVVNAIS RACREGELST CGCSRTARPK DLPRDWLWGG CGDNVEYGYR FAKEFVDARE REKNFAKGSE EQGRVLMNLQ NNEAGRRAVY KMADVACKCH GVSGSCSLKT CWLQLAEFRK VGDRLKEKYD SAAAMRVTRK GRLELVNSRF TQPTPEDLVY VDPSPDYCLR NESTGSLGTQ GRLCNKTSEG MDGCELMCCG RGYNQFKSVQ VERCHCKFHW CCFVRCKKCT EIVDQYICK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT5B, a member of the Wnt signaling pathway, has garnered significant attention in recent years due to its pivotal role in various biological processes, including development, cell differentiation, and tissue regeneration. This glycoprotein, encoded by the WNT5B gene, is involved in non-canonical Wnt signaling, which influences cellular movements and the organization of tissues during embryogenesis. Aberrant expression of WNT5B has been implicated in several pathological conditions, such as cancer metastasis, where it modulates the tumor microenvironment and contributes to malignant behaviors like invasion and migration. Researchers have explored the potential of recombinant WNT5B protein to better understand its molecular mechanisms and investigate its therapeutic applications. Producing WNT5B as a recombinant protein allows for more detailed studies on its interactions with receptors and downstream signaling pathways, offering insights into its role in both normal physiology and disease. Furthermore, as a potential target for drug development, recombinant WNT5B may provide novel strategies for therapeutic interventions in cancers and regenerative medicine. Overall, the study of recombinant WNT5B protein holds promise not only for advancing our understanding of Wnt signaling dynamics but also for developing innovative treatment approaches for various diseases.
