Analytical Data
-
Gene name
WNT5A
- Application
-
Alternative Names
WNT5A；Protein Wnt-5a
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P41221
-
Expression Region
62-380aa
-
AA Sequence
MIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRH RRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELS TCGCSRAARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGS YESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCSLKTCWLQLADFR KVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLVYIDPSPDYCV RNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH WCCYVKCKKCTEIVDQFVCKLEHHHHH
-
Molecular Weight
37 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WNT5A is a member of the Wnt signaling pathway, which plays a critical role in various biological processes, including cell proliferation, differentiation, and tissue development. Abnormalities in WNT5A signaling have been implicated in numerous diseases, particularly in cancer and developmental disorders. Research on WNT5A recombinant protein has garnered interest due to its potential therapeutic applications, especially in regenerative medicine and oncology. Understanding the structural and functional aspects of WNT5A is crucial, as it is involved in regulating non-canonical Wnt pathways, influencing cell migration and polarity. Experimental studies with recombinant WNT5A protein offer insights into its signaling mechanisms and biological effects on target cells. Furthermore, as WNT5A has been shown to affect cellular responses in various contexts, including immune modulation and tumor microenvironments, characterizing its activity could provide novel strategies for targeted therapies. The quest to harness WNT5A’s biological properties underscores its significance in advancing both basic science and clinical applications, making it a focal point for ongoing research initiatives.
