Cat: IPD-X41527

Recombinant Papio hamadryas SPACA3 Protein ,His & Myc

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Analytical Data

  • Gene name

    SPACA3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    (Sperm protein reactive with antisperm antibodies)(Sperm protein reactive with ASA)(Fragment)

  • Species

    Papio hamadryas

  • Source

    E. coli

  • Tag

    N- His & C- Myc

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    B6VH79

  • Expression Region

    87-166aa

  • Molecular Weight

    16.5 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SPACA3 (Sperm Protein Associated with the Clathrin-Acylation 3) is a recently identified protein that plays a crucial role in male fertility and sperm maturation. Research into SPACA3 is significant due to its involvement in the development and function of sperm cells, specifically in processes related to sperm-egg interaction and fertilization. Recent studies have highlighted that SPACA3 is expressed in the spermatogenic cells within the testes and is essential for the proper development of mature spermatozoa. Abnormalities in SPACA3 expression have been linked to male infertility, making it a potential biomarker for fertility assessments. Furthermore, understanding the mechanisms by which SPACA3 operates could provide insights into novel contraceptive methods and fertility treatments. Given the rising prevalence of male infertility issues globally, exploring the functions and regulatory pathways of SPACA3 could not only enhance our understanding of reproductive biology but also lead to innovative strategies for addressing fertility challenges. Thus, SPACA3 represents a promising target for further research in both basic and applied reproductive sciences.

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