Analytical Data
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基因名
PLIN1
- Application
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别名
PLIN1；PERI；PLIN；Perilipin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60240
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表达区间
411-496aa
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氨基酸序列
EPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRV
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分子量
11.2kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLIN1 (perilipin 1) is a key protein that plays a crucial role in lipid metabolism and storage within adipocytes. As a component of lipid droplets, PLIN1 regulates the accessibility of lipases to triglycerides, thus influencing lipolysis and energy homeostasis. Research has shown that PLIN1 is not only essential for normal adipocyte function but also contributes to metabolic disorders such as obesity and type 2 diabetes. The interest in PLIN1 has grown due to its potential as a therapeutic target for metabolic diseases. Recombinant PLIN1 protein studies facilitate the understanding of its structural properties, functional mechanisms, and interactions with other proteins or lipids. By producing PLIN1 in recombinant systems, researchers can analyze how alterations in PLIN1 expression or function might impact lipid metabolism, further elucidating its role in adipocyte biology and its implications in metabolic disease pathways. Overall, the investigation of recombinant PLIN1 provides valuable insights that can inform the development of novel strategies for treating dysregulated lipid metabolism.
