Analytical Data
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基因名
AMMECR1L
- Application
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别名
AMMECR1L；AMMECR1-like Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969S7
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表达区间
1-310aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMGKRRCVPPLEPKLAAGCCGVKKPKLS GSGTHSHGNQSTTVPGSSSGPLQNHQHVDSSSGRENVSDLTLGPGNSPIT RMNPASGALSPLPRPNGTANTTKNLVVTAEMCCYCFDVLYCHLYGFPQPR LPRFTNDPYPLFVTWKTGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKD SRFPPLTREELPKLFCSVSLLTNFEDASDYLDWEVGVHGIRIEFINEKGV KRTATYLPEVAKEQDWDQIQTIDSLLRKGGFKAPITSEFRKTIKLTRYRS EKVTISYAEYIASRQHCFQNGTLHAPPLYNHYS
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AMMECR1L (AMME chromosomal region 1-like protein) is a relatively novel protein that has gained attention in the context of gene therapy and regenerative medicine. Its significance arises from its association with the AMME (Amegakaryocytic thrombocytopenia, Mongolian spot, and early tooth decay) syndrome, a genetic disorder affecting hemostasis and bone development. Studies have suggested that AMMECR1L plays a crucial role in cellular processes such as cell proliferation, differentiation, and apoptosis. Given its involvement in critical biological pathways, researchers are exploring the potential of AMMECR1L as a therapeutic target for various conditions, including hematological disorders and bone regeneration. The recombinant version of AMMECR1L is being investigated for its biotechnological applications, focusing on its ability to modulate cellular functions and its potential as a biomarker for disease. Additionally, understanding the structure and function of AMMECR1L can provide insights into its mechanisms of action and its role in disease pathology, paving the way for novel therapeutic interventions. As research progresses, AMMECR1L is emerging as a candidate for innovative treatment strategies, underscoring the importance of studying its recombinant form to unlock its full therapeutic potential.
