Analytical Data
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Gene name
DSG2
- Application
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Alternative Names
(Cadherin family member 5)(HDGC)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14126
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Expression Region
50-609aa
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Molecular Weight
68.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DSG2 (Desmoglein 2) is a member of the desmoglein family, which are cadherin-like glycoproteins primarily found in desmosomes, intercellular junctions critical for cell adhesion in epithelial tissues. Understanding the structure and function of DSG2 is crucial as it plays a significant role in maintaining tissue integrity and is involved in various cellular processes, including signaling and maintaining cell shape. Research has shown that DSG2 is implicated in numerous pathological conditions, including skin disorders and cancers, making it an attractive target for therapeutic intervention. The study of DSG2 recombinant proteins has gained momentum, as these proteins can be produced in the laboratory and used to analyze the functional properties and interactions of DSG2 comprehensively. By investigating the mechanisms of DSG2 at the molecular level, researchers aim to elucidate its role in cell biology and its potential as a biomarker for disease or a target for drug development. This research not only enhances our understanding of cell adhesion mechanisms but also opens up avenues for developing novel therapeutic strategies to tackle diseases associated with DSG2 dysfunction. Overall, the focus on DSG2 recombinant proteins represents a critical intersection of molecular biology, therapeutic innovation, and disease understanding, with the potential to significantly impact clinical outcomes in conditions where DSG2 is a key player.
