Analytical Data
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Gene name
SOX9
- Application
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Alternative Names
SOX9；Transcription factor SOX-9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P48436
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Expression Region
1-509aa
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AA Sequence
MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQE NTFPKGEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSK NKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESE KRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISP NAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKA DLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPP QAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTE QLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSS YYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSPQHWEQ PVYTQLTRP
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Molecular Weight
83 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SOX9 is a transcription factor belonging to the Sox family, playing a critical role in various developmental processes, particularly in chondrogenesis and the differentiation of somatic cells. Its significance is highlighted in the context of sex determination, cell fate decisions, and stem cell maintenance. Dysregulation of SOX9 has been implicated in various diseases, including skeletal disorders and cancers, making it an important target for therapeutic interventions. The study of recombinant SOX9 protein facilitates the understanding of its functional mechanisms and interactions within cellular pathways. By producing recombinant SOX9, researchers can systematically investigate its role in gene expression regulation and cellular behavior in both normal and pathological conditions. This research background underscores the importance of SOX9 not only in developmental biology but also in the context of regenerative medicine, where it holds potential for inducing pluripotency and tissue regeneration. Understanding its structure, function, and interactions at the protein level is crucial for developing novel approaches to manipulate its activity for therapeutic purposes. Therefore, the exploration of SOX9 recombinant proteins serves as a foundational step towards advancing our understanding of its biological roles and potential applications in biomedical fields.
