Cat: PA1000-83DB

Recombinant Human AGR2 Protein,His

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Analytical Data

  • 基因名

    AGR2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    AGR2;AG2;Anterior gradient Protein 2 homolog

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O95994

  • 表达区间

    21-175aa

  • 氨基酸序列

    RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

  • 分子量

    22 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

AGR2 (anterior gradient 2) is a member of the anterior gradient family of proteins and has garnered significant interest in recent years due to its role in various biological processes and disease states, particularly in cancer. Initially identified as a protein involved in embryonic development and organogenesis, AGR2 has been linked to the regulation of epithelial cell homeostasis and differentiation. Its overexpression has been observed in various malignancies, including breast and lung cancers, correlating with aggressive tumor characteristics and poor prognostic outcomes. Given its potential as a biomarker and therapeutic target, researchers are increasingly focusing on the structural and functional analysis of recombinant AGR2 protein. The ability to produce recombinant AGR2 allows for the elucidation of its biological functions, interaction partners, and mechanisms of action at a molecular level. Additionally, understanding its molecular structure can inform potential drug design strategies aimed at inhibiting its function in cancer progression. The investigation of AGR2's role in cellular stress responses, protein folding, and secretion further emphasizes its significance in pathophysiology. Overall, the research on recombinant AGR2 protein provides a foundation for novel diagnostic and therapeutic approaches in cancer treatment, highlighting the need for continued exploration of its biological implications and clinical relevance.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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