Analytical Data
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基因名
INSL6
- Application
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别名
INSL6；RIF1；Insulin-like peptide INSL6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y581
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表达区间
1-198aa
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氨基酸序列
MPRLLRLSLL WLGLLLVRFS RELSDISSAR KLCGRYLVKE IEKLCGHANW SQFRFEEETP FSRLIAQASE KVEAYSPYQF ESPQTASPAR GRGTNPVSTS WEEAVNSWEM QSLPEYKDKK GYSPLGKTRE FSSSHNINVY IHENAKFQKK RRNKIKTLSN LFWGHHPQRK RRGYSEKCCL TGCTKEELSI ACLPYIDF
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
INSL6 (Insulin-like peptide 6) is a member of the insulin superfamily that plays a crucial role in various physiological processes, particularly in reproduction and metabolism. Initially identified in the context of testicular function, research has suggested that INSL6 may be involved in the regulation of reproductive hormones and the development of male fertility. Its expression is predominantly localized in the Leydig cells of the testes, where it is thought to influence the local endocrine environment. Additionally, INSL6 has gained attention for its potential link to metabolic conditions, including obesity and diabetes, due to its insulin-like effects. The recombinant production of INSL6 protein has opened new avenues for studying its biological functions and mechanisms. By generating large quantities of this protein through recombinant DNA technology, researchers aim to elucidate INSL6's role in cellular signaling pathways, interactions with insulin receptors, and its overall contribution to metabolic health and reproductive physiology. Understanding INSL6's structure and function could pave the way for novel therapeutic strategies targeting metabolic disorders and male infertility, making it a significant focus of ongoing research in endocrinology and reproductive biology.
