Analytical Data
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Gene name
MATN1
- Application
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Alternative Names
Cartilage matrix protein(Matrilin-1)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P21941
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Expression Region
23-496aa
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Molecular Weight
57.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MATN1, or Matrilin-1, is a member of the matrilin protein family, which plays a crucial role in the extracellular matrix and is essential for the structural integrity and function of various tissues, particularly in connective tissues like cartilage and tendons. Its unique assembly properties, as a non-collagenous component, allow it to interact with other matrix proteins, contributing to the organization and stability of the extracellular matrix. Research on MATN1 has gained momentum due to its implications in various biological processes, such as tissue development, repair, and disease pathogenesis. Alterations in MATN1 expression or mutations have been linked to several disorders, including osteoarthritis and other skeletal diseases. Therefore, studying MATN1 recombinant proteins is vital for understanding its functions, interactions, and potential therapeutic applications. By utilizing recombinant DNA technology, researchers can produce MATN1 in large quantities, facilitating detailed investigations into its biochemical properties, structural characteristics, and role in disease mechanisms. This research not only enhances our comprehension of MATN1's biological functions but also paves the way for the development of targeted strategies for treating conditions associated with its dysregulation, emphasizing its significance in both basic and applied biomedical sciences. As such, MATN1 serves as an important focus in the ongoing exploration of extracellular matrix components and their contributions to health and disease.
