Analytical Data
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Gene name
HERVK_113
- Application
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Alternative Names
HERV-K113 Gag protein (HERV-K_19p13.11 provirus ancestral Gag polyprotein) (Gag polyprotein)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62684
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Expression Region
2-666aa
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Molecular Weight
81.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HERV-K113, a member of the human endogenous retrovirus (HERV) family, has gained attention in recent years due to its potential implications in human health and disease. This retroviral element is part of the remnants of ancient viral infections that have integrated into the human genome over millions of years, leading to a complex interplay between viral sequences and human biology. Research has suggested that HERV-K113 may play a role in various pathological conditions, including certain cancers, autoimmune diseases, and neurological disorders. The study of HERV-K113 and its recombinant proteins is particularly significant because they can influence immune responses and cell signaling pathways. Understanding how HERV-K113 proteins interact with host cells may provide insights into their potential role in disease mechanisms, as well as opportunities for novel therapeutic strategies. The investigation of HERV-K113 also sheds light on the broader implications of endogenous retroviruses in human evolution and development, making it a fascinating target for both basic and applied research in virology, immunology, and molecular biology. As scientists continue to explore the functional roles of HERVs like HERV-K113, it is crucial to unravel the complexity of viral-human interactions to better understand their contributions to health and disease.
