Analytical Data
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Gene name
arsR
- Application
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Alternative Names
arsE
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Species
Escherichia coli
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P37309
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Expression Region
1-117aa
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Molecular Weight
19.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ArsR is a transcriptional regulator belonging to the ArsR/SmtB family of metal-binding proteins, primarily involved in the homeostasis of arsenic and other toxic heavy metals in various organisms, including bacteria and archaea. As a crucial element in cellular defense mechanisms, ArsR responds to the presence of arsenic by altering gene expression to mitigate its toxicity. The study of recombinant ArsR proteins has gained traction due to their role in bioremediation strategies and their potential applications in biotechnology. Understanding the structural and functional properties of ArsR can provide insights into the mechanisms of heavy metal sensing and regulation. Research has focused on the protein's ability to bind arsenic, the conformational changes it undergoes upon metal binding, and its subsequent interaction with DNA regulatory elements. Furthermore, recombinant production of ArsR facilitates studies on its biochemical properties and offers opportunities to design novel biosensors for environmental monitoring. As industrial activities contribute to arsenic pollution, recombinant ArsR proteins hold promise for developing effective biotechnological solutions to protect ecosystems and human health. Thus, elucidating the role of ArsR in metal ion regulation is not only fundamental to microbiology but also crucial for advancing environmental biotechnology and ensuring sustainable practices in metal-rich environments.
