Analytical Data
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Gene name
OPN3
- Application
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Alternative Names
Encephalopsin Panopsin
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H1Y3
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Expression Region
1-402aa
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Molecular Weight
47.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OPN3, also known as melanopsin, is a member of the opsin family of light-sensitive proteins primarily expressed in the retina. It has garnered significant interest in recent years due to its role in non-image-forming visual functions, including circadian rhythm regulation and photoperiodic responses. Research has shown that OPN3 is involved in the detection of ambient light, influencing various physiological processes such as sleep patterns, mood, and hormonal regulation. The study of recombinant OPN3 proteins has become crucial for understanding its structure-function relationship and the mechanisms underlying its phototransduction pathway. Recombination techniques allow researchers to produce OPN3 in controlled conditions, facilitating detailed biochemical analyses and functional assays. Moreover, the exploration of OPN3's potential therapeutic applications, such as in mood disorders and sleep disfunction, highlights its importance in both basic and applied science. Overall, the research on recombinant OPN3 proteins offers valuable insights into the complex interplay between light and biological systems, paving the way for advancements in neurobiology and pharmacology.
