Analytical Data
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Gene name
YEATS4
- Application
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Alternative Names
Glioma-amplified sequence 41
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95619
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Expression Region
1-227aa
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Molecular Weight
53.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
YEATS4 is a member of the YEATS family of proteins, which are implicated in various cellular processes, including gene regulation and chromatin remodeling. Initially, the interest in YEATS4 arose from its association with histone acetylation and the modulation of transcriptional activities, particularly in cancer biology. Studies have shown that YEATS4 can interact with specific acetylated lysine residues on histones, suggesting a role in recognizing and binding to modified chromatin, thereby influencing gene expression patterns. Furthermore, aberrant expression of YEATS4 has been linked to several types of cancers, highlighting its potential as a biomarker and therapeutic target. Recent research has focused on the structural characterization of YEATS4 to better understand its molecular mechanisms and functional implications. By investigating the protein's structure and interactions at a molecular level, scientists aim to elucidate its role in epigenetic regulation and its contribution to disease pathogenesis. This research is pivotal, as it can lead to the development of novel strategies for cancer treatment and provide insights into the fundamental processes of cellular regulation. Understanding YEATS4's function not only contributes to the broader field of epigenetics but also opens avenues for targeted therapies that could mitigate its oncogenic effects.
