Analytical Data
-
基因名
UBE2D3
- Application
-
别名
Ubiquitin carrier protein D3Ubiquitin-conjugating enzyme E2(17)KB 3Ubiquitin-conjugating enzyme E2-17KDA 3Ubiquitin-protein ligase D3
-
种属
Human
-
表达系统
E. coli
-
标签
N- His-SUMO
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P61077
-
表达区间
1-147aa
-
分子量
32.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UBE2D3, a member of the E2 ubiquitin-conjugating enzyme family, plays a crucial role in the ubiquitin-proteasome system, which regulates protein degradation and various cellular processes such as cell cycle progression, apoptosis, and DNA repair. Research has highlighted UBE2D3's involvement in the ubiquitination of key substrates, influencing signal transduction pathways and contributing to the maintenance of cellular homeostasis. Given its significant role in regulating protein stability and its implication in various diseases, including cancer, neurological disorders, and viral infections, the recombinant expression and characterization of UBE2D3 have emerged as a vital area of investigation. By generating recombinant UBE2D3, researchers aim to better understand its enzymatic mechanisms, substrate specificity, and regulatory interactions. Furthermore, understanding the structural and functional aspects of UBE2D3 may pave the way for the development of novel therapeutic strategies targeting the ubiquitin-proteasome pathway, potentially offering new insights for disease treatment and management. The ongoing research into UBE2D3 underscores its potential as a biomarker and therapeutic target, as well as its importance in elucidating the complexities of cellular regulation through ubiquitination.
