Analytical Data
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Gene name
TUSC2
- Application
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Alternative Names
Fusion 1 protein
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75896
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Expression Region
1-110aa
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Molecular Weight
38.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TUSC2 (Tumor Suppressor Candidate 2) is a gene located on chromosome 3p21.3, a region frequently associated with deletions in various types of cancers, including lung and breast cancer. Research has indicated that TUSC2 functions as a tumor suppressor, playing a critical role in inhibiting cell proliferation and promoting apoptosis in malignant cells. The protein encoded by TUSC2 has been shown to have anti-cancer properties, making it a promising candidate for gene therapy applications. Scientists have been investigating the potential of recombinant TUSC2 protein for therapeutic use, particularly its ability to re-establish normal apoptotic pathways in tumor cells. Studies have revealed that TUSC2 might interact with several cellular pathways, influencing factors such as DNA repair, cell cycle regulation, and responses to cellular stress. Efforts to produce TUSC2 as a recombinant protein have focused on optimizing its expression in various systems, including bacterial and mammalian cells. The availability of recombinant TUSC2 opens avenues for in-depth studies into its mechanism of action, as well as its potential as a biomarker for cancer diagnosis and prognosis. Moreover, preclinical trials using TUSC2 gene delivery have shown promise in selectively targeting cancer cells, underscoring the importance of TUSC2 in cancer research and its potential role in developing future therapies. Overall, the study of TUSC2 and its recombinant protein continues to provide insights into cancer biology and therapeutic innovation, highlighting its significance as a potential tool in the fight against cancer.
