Analytical Data
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Gene name
CNTN4/Contactin-4
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简介
The CNTN4/Contactin-4 protein is a member of the contactin family and plays a key role in promoting cell surface interactions critical for nervous system development. It has proven neurite growth-promoting activity, assisting in the complex processes involved in neuronal growth. CNTN4/Contactin-4 Protein, Human (sf9, His) is the recombinant human-derived CNTN4/Contactin-4 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- Application
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Alternative Names
Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2
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Species
Human
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Source
Baculovirus
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IWV2-1
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Expression Region
D19-S1000
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Protein Length
Full Length of Contactin-4
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Molecular Weight
120-130 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Contactin-4 (CNTN4) is a member of the contactin family of neuronal cell adhesion molecules, playing a crucial role in the development and function of the nervous system. It is predominantly expressed in the central nervous system and is involved in various processes, including neuronal differentiation, axon guidance, and synaptic plasticity. Recent research has highlighted CNTN4's significance in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia, as genetic variations affecting this protein have been linked to altered neuronal connectivity and cognitive functions. The study of recombinant CNTN4 proteins aims to elucidate their structural and functional properties, providing insights into their role in cell signaling and interactions with other neuronal proteins. By producing and characterizing these recombinant proteins, researchers seek to develop therapeutic strategies that target CNTN4-related pathways, enhancing our understanding of its implications in neurodevelopment and potential interventions for related disorders. This research is vital for advancing the field of neuroscience and developing novel approaches to treat conditions associated with CNTN4 dysfunction.
