Analytical Data
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基因名
FOLR4
- Application
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别名
Folbp3; IZUMO1R; JUNO; Sperm-egg fusion protein Juno; Folate receptor delta; IZUMO1 receptor protein JUNO
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9EQF4
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表达区间
Cys56~Pro234
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分子量
25kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FOLR4 (Folate receptor 4) is a member of the folate receptor family, which plays a crucial role in folate uptake and transport in various cell types. It is primarily expressed in the placenta, kidney, and certain cancer tissues, making it a potential target for therapeutic interventions, particularly in cancer research. Studies have demonstrated that FOLR4 is involved in important biological processes, including cell proliferation, differentiation, and immune response modulation. Due to its overexpression in several tumors, such as ovarian cancer and certain leukemias, FOLR4 has garnered significant attention as a biomarker for cancer diagnosis and prognosis. The study of recombinant FOLR4 proteins provides valuable insights into the receptor's structure-function relationships, enhancing our understanding of its mechanisms in cellular signaling pathways. Additionally, the development of FOLR4-targeted therapies, such as antibody-drug conjugates, showcases its potential as a novel approach for targeted cancer treatment. Given the impact of FOLR4 in both health and disease, ongoing research into its recombinant forms aims to unlock new diagnostic and therapeutic avenues in oncology and beyond.
