Analytical Data
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Gene name
KRT25
- Application
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Alternative Names
KRT25A; CK-25; K25; Cytokeratin-25; Keratin, type I cytoskeletal 25; Type I inner root sheath-specific keratin-K25irs1
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8VCW2
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Expression Region
Met1~Asn446
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Molecular Weight
53kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KRT25, or Keratin 25, is part of the keratin family of proteins, which play a critical role in the structural integrity and function of epithelial cells. Research into KRT25 has gained prominence due to its potential implications in skin health and diseases, particularly in conditions characterized by keratinocyte dysfunction, such as psoriasis and other dermatological disorders. In recent years, advancements in molecular biology have facilitated the exploration of KRT25's role in cellular processes, including proliferation, differentiation, and apoptosis of keratinocytes. Studies have indicated that KRT25 expression patterns may be altered in various pathological conditions, suggesting its involvement in the etiology of certain skin diseases. Additionally, understanding the biochemical properties and regulatory mechanisms of KRT25 can provide insights into novel therapeutic targets for skin cancers and regenerative medicine. The production and characterization of recombinant KRT25 protein through techniques such as recombinant DNA technology allow for a detailed study of its functional properties and interactions with other cellular components. This research not only aims to elucidate the precise biological functions of KRT25 but also seeks to explore its potential utility in developing biomarkers for skin diseases and evaluating treatment responses. Overall, KRT25 represents a significant focus within keratin research, with promising implications for dermatological health and disease management.
