Analytical Data
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基因名
KRT25
- Application
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别名
KRT25A; CK-25; K25; Cytokeratin-25; Keratin, type I cytoskeletal 25; Type I inner root sheath-specific keratin-K25irs1
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8VCW2
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表达区间
Met1~Asn446
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分子量
53kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT25, or Keratin 25, is part of the keratin family of proteins, which play a critical role in the structural integrity and function of epithelial cells. Research into KRT25 has gained prominence due to its potential implications in skin health and diseases, particularly in conditions characterized by keratinocyte dysfunction, such as psoriasis and other dermatological disorders. In recent years, advancements in molecular biology have facilitated the exploration of KRT25's role in cellular processes, including proliferation, differentiation, and apoptosis of keratinocytes. Studies have indicated that KRT25 expression patterns may be altered in various pathological conditions, suggesting its involvement in the etiology of certain skin diseases. Additionally, understanding the biochemical properties and regulatory mechanisms of KRT25 can provide insights into novel therapeutic targets for skin cancers and regenerative medicine. The production and characterization of recombinant KRT25 protein through techniques such as recombinant DNA technology allow for a detailed study of its functional properties and interactions with other cellular components. This research not only aims to elucidate the precise biological functions of KRT25 but also seeks to explore its potential utility in developing biomarkers for skin diseases and evaluating treatment responses. Overall, KRT25 represents a significant focus within keratin research, with promising implications for dermatological health and disease management.
