Analytical Data
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Gene name
FABP7
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简介
FABP7 Protein, Human expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms[1].
- Application
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Alternative Names
rHuFABP7, His; Fatty Acid-Binding Protein Brain; B-FABP; Brain-Type Fatty Acid-Binding Protein
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15540-1
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Expression Region
M1-A132
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Protein Length
Full Length of Isoform-1
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Molecular Weight
16 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fatty acid-binding protein 7 (FABP7), also known as brain-type FABP, plays a critical role in the transport and metabolism of fatty acids in the central nervous system. It is predominantly expressed in the brain, particularly in astrocytes and neural progenitor cells, where it is involved in neurodevelopment, myelination, and the regulation of neuroinflammation. Dysregulation of FABP7 has been implicated in various neurodegenerative diseases and psychiatric disorders, including Alzheimer's disease, schizophrenia, and depression. Given its significant influence on brain function and potential as a therapeutic target, research has focused on the production and characterization of recombinant FABP7 proteins. These recombinant proteins facilitate the study of FABP7's molecular mechanisms and interactions with fatty acids and other ligands. Furthermore, understanding the structure-function relationship of FABP7 through these studies may offer insights into its role in brain pathology and aid in the development of novel strategies for intervention in related disorders. The precise characterization of FABP7, including its binding affinities and dynamics, is essential for expanding our knowledge and paving the way for therapeutic innovations targeting this important protein in neurological health and disease.
