Analytical Data
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基因名
MAGEB16
- Application
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9CWV4
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表达区间
Met1~Val363
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分子量
65kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MAGEB16, part of the MAGE (Melanoma Antigen Gene) family, is a gene primarily expressed in various cancer types, particularly melanoma. This gene encodes for a protein that is not typically present in normal adult tissues, making it a valuable target for cancer immunotherapy. The expression of MAGEB16 is closely associated with tumor progression, and its presence has been linked to poor prognosis in certain cancers. Research has focused on characterizing the structure and function of the MAGEB16 protein to understand its role in tumor biology and to explore its potential as a biomarker for cancer diagnosis and therapy. Furthermore, the immunogenic properties of MAGEB16 make it an attractive candidate for vaccine development, as it could elicit specific immune responses against tumor cells. Studies have also examined the regulatory mechanisms governing MAGEB16 expression, revealing insights into epigenetic factors that might contribute to its expression in malignancies. Overall, MAGEB16 represents a significant focal point in the search for targeted cancer therapies, due to its restricted expression profile and potential involvement in immune evasion by tumors. Researchers continue to investigate how MAGEB16 can be leveraged in combination with existing therapies to enhance treatment efficacy and improve outcomes for cancer patients.
