Analytical Data
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Gene name
RGC32
- Application
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Alternative Names
RGCC; C13orf15; Regulator of cell cycle RGCC
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H4X1
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Expression Region
Met1~Met137
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Molecular Weight
18.3kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RGC32, or Regulator of G Protein Signaling 32, is a member of the RGS family, which plays a crucial role in modulating G protein-mediated signaling pathways. This protein is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis, making it significant in both normal physiological functions and in the pathology of several diseases, particularly cancers. Dysregulation of RGC32 expression has been implicated in tumorigenesis, where abnormal G protein signaling contributes to uncontrolled cell growth and survival. Recent studies have focused on understanding the molecular mechanisms by which RGC32 regulates these pathways, including its interactions with specific G proteins and its implications in signal transduction. Moreover, the recombinant expression of RGC32 protein offers valuable insights into its structural characteristics and functional roles. By utilizing techniques such as protein purification and functional assays, researchers aim to decipher the binding properties and biological effects of RGC32. Additionally, investigating its role in various cancers could potentially lead to the development of novel therapeutic strategies targeting RGC32-related pathways, thereby opening new avenues for cancer treatment. Overall, the study of RGC32 is critical for advancing our understanding of G protein signaling dynamics and its implications in health and disease.
