Analytical Data
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Gene name
VPS13D
- Application
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Species
Mouse
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
B1ART2
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Expression Region
Pro730~Gln1062
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Molecular Weight
69kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
VPS13D is a member of the VPS13 family, which plays crucial roles in organelle contact sites and lipid transport, contributing to cellular homeostasis. Its significance has become increasingly apparent in the context of neurodegenerative diseases, particularly Parkinson's disease, where mutations in VPS13D have been linked to susceptibility. Research indicates that VPS13D is involved in the regulation of mitochondrial function and lipid metabolism, suggesting a protective role against cellular stress. Additionally, its interactions with various proteins within the endosomal-lysosomal pathway highlight its potential as a therapeutic target. Understanding the structure and function of VPS13D is critical for elucidating its role in cellular physiology and pathology, paving the way for novel approaches in the treatment of relevant disorders. The ongoing study of VPS13D reconstituted proteins aims to uncover the detailed mechanisms of its action, providing insights that could lead to innovative strategies for managing neurodegeneration and related conditions.
