Cat: IPD-X27346

Recombinant Mouse REG-2 Protein (HEK293),hFc

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Analytical Data

  • Gene name

    REG-2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Lithostathine-2; REG-2; PSP; PTP

  • Species

    Mouse

  • Source

    HEK293

  • Tag

    C-hFc

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q08731

  • Expression Region

    M1-A173

  • Protein Length

    Full Length

  • Molecular Weight

    45.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

REG-2, also known as regenerating gene protein 2, is a crucial member of the REG family of proteins, which are primarily expressed in the pancreas and intestines. This protein is implicated in various physiological processes, including cell proliferation, regeneration, and inflammation. Research on REG-2 has gained momentum due to its potential role in digestive disorders, such as pancreatitis and inflammatory bowel diseases, where its expression levels are often altered. Additionally, REG-2 is considered a marker for pancreatic ductal adenocarcinoma, highlighting its significance in cancer research. Its multifaceted functions make it a target of interest for therapeutic strategies aimed at promoting tissue regeneration and modulating inflammatory responses. Ongoing studies focus on elucidating the molecular mechanisms underlying REG-2 activity, as well as its interactions with other signaling pathways. This research not only enhances our understanding of REG-2's role in health and disease but also opens avenues for developing innovative treatments that harness its regenerative properties.

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