Analytical Data
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基因名
HCRP1
- Application
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别名
PQBP2; VPS37A; Vacuolar Protein Sorting 37 Homolog A; Polyglutamine Binding Protein 2; ESCRT-I complex subunit VPS37A
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NEZ2
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表达区间
Met1~Leu397
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分子量
48kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HCRP1, or Human Cytokine Response Protein 1, is a crucial component in the study of immune responses and cytokine signaling pathways. This protein has garnered significant attention due to its role in regulating inflammatory responses, which is essential for maintaining immune homeostasis and responding to infections. Research has shown that HCRP1 interacts with various cytokines and signaling molecules, thus influencing the outcomes of immune cell activation and differentiation. Dysregulation of HCRP1 expression is linked to several pathological conditions, including autoimmune diseases, chronic inflammatory disorders, and cancers. As a result, understanding the structure and function of HCRP1 at the molecular level is vital for elucidating its role in these diseases. The development of recombinant HCRP1 proteins facilitates detailed studies into its functional mechanisms and potential therapeutic applications. By producing HCRP1 in a recombinant form, researchers can explore its interactions with other proteins, its role in cell signaling pathways, and its potential as a biomarker or therapeutic target. This ongoing research highlights the importance of HCRP1 in both basic science and clinical settings, aiming to provide insights that could lead to innovative treatments for immune-related disorders.












