Analytical Data
-
Gene name
GPAM
- Application
-
Alternative Names
GPAT1
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9HCL2
-
Expression Region
Leu594~Leu828
-
Molecular Weight
31kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of GPAM (glycerol-3-phosphate acyltransferase) recombinant protein is rooted in the growing understanding of lipid metabolism and its implications in health and disease. GPAM is a key enzyme in the glycerolipid synthesis pathway, catalyzing the conversion of glycerol-3-phosphate into lysophosphatidic acid, which is a crucial step in the biosynthesis of triglycerides and phospholipids. Dysregulation of GPAM has been linked to various metabolic disorders, including obesity, diabetes, and cardiovascular diseases, highlighting its potential as a therapeutic target. Researchers are increasingly focused on producing recombinant GPAM to study its structure-function relationships, enzymatic activity, and regulatory mechanisms in detail. By utilizing recombinant DNA technology, GPAM can be expressed in host systems, allowing for the generation of large quantities of the protein for biochemical characterization and potential drug discovery. Additionally, understanding GPAM's role in lipid metabolism may offer insights into novel strategies for managing metabolic diseases, making it a significant area of research in molecular biology and pharmacology.
