Analytical Data
-
Gene name
MTF2
- Application
-
Alternative Names
M96; PCL2; Polycomb-Like 2; Metal-response element DNA-binding protein M96; Metal regulatory transcription factor 2
-
Species
Human
-
Source
E. coli
-
Tag
N- His & GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y483
-
Expression Region
Met1~Ser593
-
Molecular Weight
97kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MTF2 (Metal-response element-binding transcription factor 2) is a member of the MTF family of transcription factors, primarily known for its role in cellular response to metal ions, particularly cadmium. It is involved in regulating various biological processes, including cell growth, differentiation, and apoptosis. The significance of MTF2 in cancer biology has garnered attention, as its dysregulation has been linked to tumor progression and metastasis. Recent studies have highlighted that MTF2 might play a pivotal role in modulating gene expression in response to oxidative stress and heavy metal exposure, contributing to the cellular defense mechanism. Researchers are increasingly focusing on the recombinant expression of MTF2 to understand its structural and functional properties, which may provide insights into its mechanism of action and potential therapeutic applications. The development of MTF2 recombinant proteins is crucial for elucidating these functions as well as for exploring its interaction with other cellular proteins. Thus, the study of MTF2 not only enhances our understanding of metal ion homeostasis in cells but also suggests potential pathways for targeted therapies in metal-induced disorders and cancers associated with MTF2 dysregulation.
