Analytical Data
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基因名
MTF2
- Application
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别名
M96; PCL2; Polycomb-Like 2; Metal-response element DNA-binding protein M96; Metal regulatory transcription factor 2
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y483
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表达区间
Met1~Ser593
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分子量
97kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MTF2 (Metal-response element-binding transcription factor 2) is a member of the MTF family of transcription factors, primarily known for its role in cellular response to metal ions, particularly cadmium. It is involved in regulating various biological processes, including cell growth, differentiation, and apoptosis. The significance of MTF2 in cancer biology has garnered attention, as its dysregulation has been linked to tumor progression and metastasis. Recent studies have highlighted that MTF2 might play a pivotal role in modulating gene expression in response to oxidative stress and heavy metal exposure, contributing to the cellular defense mechanism. Researchers are increasingly focusing on the recombinant expression of MTF2 to understand its structural and functional properties, which may provide insights into its mechanism of action and potential therapeutic applications. The development of MTF2 recombinant proteins is crucial for elucidating these functions as well as for exploring its interaction with other cellular proteins. Thus, the study of MTF2 not only enhances our understanding of metal ion homeostasis in cells but also suggests potential pathways for targeted therapies in metal-induced disorders and cancers associated with MTF2 dysregulation.
