Analytical Data
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Gene name
PTTG1IP
- Application
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Alternative Names
PBF; C21orf1; C21orf3; Pituitary tumor-transforming gene protein-binding factor
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53801
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Expression Region
Gln33~Glu96
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Molecular Weight
37kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTTG1IP (PTTG1 interacting protein) is a crucial regulator involved in various cellular processes, particularly those related to cell cycle regulation and cancer biology. It interacts with the securin protein PTTG1, which plays a significant role in mitosis and the prevention of premature sister chromatid separation. Aberrations in PTTG1IP expression have been linked to several cancers, making it a potential biomarker and therapeutic target. Researchers aim to understand the molecular mechanisms by which PTTG1IP modulates cell proliferation and apoptosis, as well as its implications in tumorigenesis. Recombinant PTTG1IP protein production allows scientists to conduct functional assays and structural analyses, which facilitate the study of its interactions with other proteins and its role in cancer progression. Understanding the biological functions and pathways associated with PTTG1IP can lead to novel approaches for cancer treatment, highlighting its significance in oncological studies. Overall, PTTG1IP serves as a promising candidate in the search for effective strategies in cancer therapy, warranting further exploration of its role in cellular dynamics and tumor biology.
