Analytical Data
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Gene name
UQCRC2
- Application
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Alternative Names
QCR2; UQCR2; Cytochrome b-c1 complex subunit 2, mitochondrial; Complex III subunit 2; Core protein II
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9DB77
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Expression Region
Ser15~Leu453
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Molecular Weight
50kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UQCRC2, or Ubiquinol-cytochrome c reductase core protein 2, is a critical component of the mitochondrial respiratory chain, specifically part of Complex III, which plays a pivotal role in cellular energy production through oxidative phosphorylation. This protein is involved in the electron transfer process, facilitating the reduction of cytochrome c and the subsequent generation of ATP, necessary for various cellular functions. Research has increasingly focused on UQCRC2 due to its potential implications in various diseases, including mitochondrial disorders, neurodegenerative diseases, and cancers, where mitochondrial dysfunction is often a contributing factor. Understanding the structure and function of UQCRC2 can provide insights into the mechanisms underlying these conditions and may aid in the development of therapeutic strategies. Recent advances in recombinant protein technology have enabled the production and characterization of UQCRC2, allowing scientists to explore its biochemical properties, interactions with other mitochondrial components, and its regulation under different physiological and pathological conditions. The study of UQCRC2 not only enhances our comprehension of mitochondrial biology but also opens avenues for targeted interventions in diseases where mitochondrial dysfunction is a hallmark.
