Cat: IPD-X39213

Recombinant Human CDH18 Protein,His

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Analytical Data

  • 基因名

    CDH18

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CDH14; EY-Cadherin

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q13634

  • 表达区间

    Gly54~Phe268

  • 分子量

    32kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CDH18, or Cadherin 18, is a member of the cadherin superfamily, which is essential for cell adhesion and is vital in processes such as tissue development and maintenance. The study of CDH18 recombinant protein has gained significant attention due to its potential role in neurodevelopmental processes and various neuropsychiatric disorders. Research indicates that CDH18 is prominently expressed in the central nervous system, particularly in regions associated with cognitive functions and synaptic plasticity. Its involvement in the formation and stabilization of synapses suggests that disruptions in its expression or function could be linked to conditions like autism spectrum disorders and schizophrenia. Moreover, understanding the structural and functional properties of CDH18 through recombinant protein studies can provide insights into its mechanistic roles in cell-cell interactions and signaling pathways. This research is pivotal to unraveling the complexities of neurological diseases and could lead to the development of targeted therapies aimed at restoring normal cadherin function. Furthermore, CDH18's unique expression pattern and interaction with other signaling molecules position it as a potential biomarker for neurodevelopmental research. Hence, the exploration of CDH18 recombinant protein not only enhances our understanding of fundamental biological processes but also opens avenues for innovative therapeutic strategies in treating neurodevelopmental disorders.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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