Analytical Data
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基因名
ATP11B
- Application
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别名
ATPIF; ATPIR; Probable Phospholipid-Transporting ATPase IF; P4-ATPase flippase complex alpha subunit ATP11B
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2G3
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表达区间
Gln78~Asn323
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ATP11B is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in various cellular processes, including lipid transport, drug resistance, and membrane dynamics. This protein is notable for its involvement in cellular homeostasis and its potential implications in disease, particularly in cancer and immune responses. Research on ATP11B has gained momentum due to its unique structural features and functional importance in transporting phospholipids across cellular membranes. Previous studies have indicated that ATP11B may influence the function of immune cells and contribute to the development of drug resistance in cancer therapies by modulating lipid composition in the membrane, which is critical for altering cell signaling pathways. As a result, the characterization of ATP11B and the generation of recombinant protein for further study has become a focus for understanding its molecular mechanisms and roles in health and disease. By producing ATP11B as a recombinant protein, researchers aim to elucidate its functional properties, interactions with other cellular components, and potential as a therapeutic target. This research could pave the way for developing novel strategies to combat diseases associated with ATP11B dysregulation.
