Analytical Data
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Gene name
SOX4
- Application
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Alternative Names
EVI16; Transcription factor SOX-4
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q06831
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Expression Region
Gly194~Tyr440
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Molecular Weight
29kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SOX4, a member of the SRY-related HMG box (SOX) family of transcription factors, plays a critical role in various biological processes, including embryonic development, cell differentiation, and tumorigenesis. Dysregulation of SOX4 has been implicated in several cancers, such as breast, prostate, and lung cancer, where it often promotes cell proliferation and metastasis. Given its significance in both normal physiology and disease pathology, the study of recombinant SOX4 protein has gained momentum. The ability to produce SOX4 in a recombinant form allows researchers to investigate its structural properties, binding interactions, and functional roles in cellular contexts. Understanding SOX4's mechanisms of action can provide insights into its potential as a therapeutic target or biomarker in cancer treatment. Advances in protein expression systems, like bacterial, yeast, or mammalian cell cultures, facilitate the efficient production of SOX4 for various applications, including high-throughput screening, structural biology studies, and functional assays. Collectively, the investigation of recombinant SOX4 protein paves the way for novel approaches in understanding its role as a modulator of gene expression and its impact on oncogenic pathways, ultimately contributing to the development of targeted therapeutic strategies.
