Analytical Data
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基因名
SOX14
- Application
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别名
SOX28; SRY-box 14; Transcription factor SOX-14
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95416
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表达区间
Met1~Met240
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOX14, a member of the SRY-related high mobility group (HMG) box family of transcription factors, plays a crucial role in the development and differentiation of various cell types, particularly in the nervous system. Its expression is primarily observed in the central nervous system and has been implicated in neurogenesis and the maintenance of neural progenitor cells. Recent studies suggest that SOX14 may influence critical biological processes such as cell fate determination and neuronal connectivity. Dysregulation of SOX14 has been associated with various neurodevelopmental disorders, highlighting its potential significance in psychiatric conditions. Given its pivotal functions, researchers are increasingly focusing on understanding the molecular mechanisms by which SOX14 regulates gene expression and interacts with other transcription factors. The study of SOX14 recombinant protein allows for in-depth investigation of its structural properties, binding affinities, and functional interactions within cellular contexts. This research can provide valuable insights into the role of SOX14 in development and disease, as well as inform potential therapeutic strategies for neurodevelopmental disorders linked to its dysfunction. Overall, the exploration of SOX14 and its recombinant protein holds promise for advancing our understanding of brain development and the molecular underpinnings of related pathologies.
