Analytical Data
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Gene name
SOX14
- Application
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Alternative Names
SOX28; SRY-box 14; Transcription factor SOX-14
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95416
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Expression Region
Met1~Met240
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Molecular Weight
33kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SOX14, a member of the SRY-related high mobility group (HMG) box family of transcription factors, plays a crucial role in the development and differentiation of various cell types, particularly in the nervous system. Its expression is primarily observed in the central nervous system and has been implicated in neurogenesis and the maintenance of neural progenitor cells. Recent studies suggest that SOX14 may influence critical biological processes such as cell fate determination and neuronal connectivity. Dysregulation of SOX14 has been associated with various neurodevelopmental disorders, highlighting its potential significance in psychiatric conditions. Given its pivotal functions, researchers are increasingly focusing on understanding the molecular mechanisms by which SOX14 regulates gene expression and interacts with other transcription factors. The study of SOX14 recombinant protein allows for in-depth investigation of its structural properties, binding affinities, and functional interactions within cellular contexts. This research can provide valuable insights into the role of SOX14 in development and disease, as well as inform potential therapeutic strategies for neurodevelopmental disorders linked to its dysfunction. Overall, the exploration of SOX14 and its recombinant protein holds promise for advancing our understanding of brain development and the molecular underpinnings of related pathologies.
