Analytical Data
-
Gene name
SOX11
- Application
-
Alternative Names
Transcription factor SOX-11
-
Species
Human
-
Source
E. coli
-
Tag
N- His & GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P35716
-
Expression Region
Met1~Glu224
-
Molecular Weight
54kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SOX11 is a member of the SRY (Sex-determining Region Y)-related HMG-box (SOX) transcription factor family, playing a crucial role in embryonic development and cell differentiation. Its involvement has been particularly noted in various cancers, including lymphoid malignancies, where it is often associated with poor prognosis. The expression of SOX11 is frequently upregulated in certain types of tumors, indicating its potential role in tumorigenesis and progression. Research has focused on understanding the molecular mechanisms of SOX11, including its regulatory pathways and target genes, to elucidate its specific functions in cancer biology. The production of recombinant SOX11 protein has become an essential tool for this research, enabling scientists to conduct detailed studies on its structural properties, binding affinities, and functional roles in cellular processes. By utilizing techniques such as protein expression and purification, researchers can investigate how SOX11 interacts with other proteins and DNA, providing insights that could lead to novel therapeutic strategies. The study of SOX11 as a recombinant protein thus holds significant promise for advancing our understanding of its contributions to tumor development and potential as a therapeutic target.
