Analytical Data
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基因名
SOX11
- Application
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别名
Transcription factor SOX-11
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35716
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表达区间
Met1~Glu224
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分子量
54kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOX11 is a member of the SRY (Sex-determining Region Y)-related HMG-box (SOX) transcription factor family, playing a crucial role in embryonic development and cell differentiation. Its involvement has been particularly noted in various cancers, including lymphoid malignancies, where it is often associated with poor prognosis. The expression of SOX11 is frequently upregulated in certain types of tumors, indicating its potential role in tumorigenesis and progression. Research has focused on understanding the molecular mechanisms of SOX11, including its regulatory pathways and target genes, to elucidate its specific functions in cancer biology. The production of recombinant SOX11 protein has become an essential tool for this research, enabling scientists to conduct detailed studies on its structural properties, binding affinities, and functional roles in cellular processes. By utilizing techniques such as protein expression and purification, researchers can investigate how SOX11 interacts with other proteins and DNA, providing insights that could lead to novel therapeutic strategies. The study of SOX11 as a recombinant protein thus holds significant promise for advancing our understanding of its contributions to tumor development and potential as a therapeutic target.
