Cat: IPD-X39196

Recombinant Human SOX7 Protein,His

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Analytical Data

  • Gene name

    SOX7

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Transcription factor SOX-7

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BT81

  • Expression Region

    Gln217~Ser388

  • Molecular Weight

    25kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SOX7 is a member of the SRY-related high-mobility group (HMG) box transcription factor family, playing a crucial role in various biological processes, including embryonic development and cellular differentiation. Its expression pattern is tightly regulated during early development and across different adult tissues, indicating its significance in multiple physiological functions. Alterations in SOX7 expression have been linked to various diseases, including cancer, where it may act as a tumor suppressor. Additionally, studies suggest that SOX7 is involved in the regulation of stem cell pluripotency and lineage commitment. Given its pivotal role in these biological contexts, the recombinant expression of SOX7 protein has become an important focus for research. By producing SOX7 as a recombinant protein, researchers aim to elucidate its molecular mechanisms and interactions in cellular pathways. This can help in understanding its function in stem cell biology and tumorigenesis, potentially leading to novel therapeutic strategies. The ability to study SOX7 in vitro provides insights into its role as a transcription factor and allows for the exploration of its genetic targets and pathways, thus contributing to the broader understanding of its implications in health and disease.

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