Analytical Data
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Gene name
NOV
- Application
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Alternative Names
CCN3; IGFBP9; NOVH; IBP-9; Insulin-like growth factor-binding protein 9; Protein NOV homolog
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9QZQ5
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Expression Region
Ala156~Met351
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Molecular Weight
29kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NOV (Nephroblastoma Overexpressed Gene) is a member of the CCN family of proteins, which are known for their role in cellular processes such as proliferation, differentiation, and survival. Originally identified as a gene overexpressed in nephroblastoma, NOV has garnered attention for its involvement in various physiological and pathological processes, including fibrosis, angiogenesis, and tumor progression. Research has shown that NOV can modulate extracellular matrix components and interact with growth factor signaling pathways, making it a critical player in tissue remodeling and repair. Its expression levels and functional roles have been implicated in diverse conditions, ranging from cancer to cardiovascular diseases. Given its multifaceted roles in both normal physiology and disease states, NOV represents a promising target for therapeutic interventions. Ongoing studies are focused on elucidating the precise mechanisms of NOV's action, exploring its potential as a biomarker for specific diseases, and investigating its therapeutic applications in regenerative medicine and oncology. Understanding the complex biology of NOV could lead to significant advancements in treatment strategies for various diseases where its dysregulation plays a crucial role.
