Analytical Data
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Gene name
CBLN1
- Application
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Alternative Names
CER; Precerebellin
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P23435
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Expression Region
Gln22~Leu193
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Molecular Weight
49kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CBLN1 (Cerebellin 1) is a protein that plays a crucial role in synaptic function and is primarily associated with the nervous system, particularly in the cerebellum where it is involved in synaptic adhesion and neurotransmission. Research on CBLN1 has gained significant attention due to its potential implications in various neurological disorders, including autism spectrum disorders, schizophrenia, and intellectual disabilities. Mutations or dysregulation of CBLN1 expression have been linked to impaired synaptic connections and altered neuronal communication, highlighting its importance in maintaining cognitive functions. The study of recombinant CBLN1 proteins is essential for elucidating its structure-function relationships and understanding how it interacts with other synaptic proteins. By producing recombinant CBLN1 in a controlled laboratory setting, researchers can investigate its biochemical properties, binding affinities, and functional roles in cellular models. Furthermore, insights gained from recombinant CBLN1 studies may lead to the development of novel therapeutic strategies aimed at restoring synaptic function in diseases associated with CBLN1 dysregulation. As such, ongoing research is focused on characterizing the effects of CBLN1 on neural circuitry and exploring its potential as a biomarker or therapeutic target in neurodevelopmental and psychiatric conditions.
