Analytical Data
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Gene name
FOXE3
- Application
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Alternative Names
FOX-E3; FKHL12; FREAC8; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9QY14
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Expression Region
Asn110~Leu288
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Molecular Weight
22kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXE3 is a member of the forkhead box (FOX) family of transcription factors, playing a crucial role in the development and maintenance of various tissues, particularly the thyroid gland and the eye. Recent studies have highlighted its significance in regulating gene expression related to cellular differentiation and organogenesis. Alterations in FOXE3 expression have been associated with congenital hypothyroidism and ocular defects, underscoring its potential as a biomarker for these conditions. Moreover, FOXE3 has been implicated in various cancers, suggesting its role in tumorigenesis and progression. Research on FOXE3 recombinant protein has gained traction as scientists aim to understand its structure-function relationships, post-translational modifications, and interactions with other proteins. This knowledge is vital for uncovering the molecular mechanisms underlying FOXE3-related pathologies and could lead to the development of targeted therapeutic strategies. Overall, the investigation of FOXE3 and its recombinant protein serves as a promising avenue for advancing our understanding of developmental biology and disease mechanisms, with potential implications in clinical diagnostics and treatment.
